UK NEUROINFLAMMATORY REPOSITORY (UKNR)
A national clinical data resource for neuroinflammatory disease
The UK Neuroinflammatory Repository (UKNR) is a Cambridge-led national initiative building a secure, structured clinical data resource for people living with MS and related neuroimmunological conditions across the UK.
It is designed to enable better understanding of disease, treatment response, and long-term outcomes — while keeping all data within secure NHS environments.
A NATIONALLY GOVERNED RESOURCE
UKNR is overseen by a Scientific Leadership Committee including:
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Senior clinical academic Chair in MS/neuroimmunology
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NHS R&D representation
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UK neurologists from major MS centres
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People living with MS (PPIE members)
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MS charity representatives
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UK MS trials and registry consortium representatives
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Data custodians, scientific experts, and project-specific specialists
WHAT MAKES UKNR DIFFERENT?
UKNR brings together structured clinical data from MS services across the UK into a consistent, analysable format.
Work is currently underway to integrate data across participating centres, with planned linkage to GP records to provide a more complete view of patient health across care settings.
SECURE, NHS-BASED RESEARCH
UKNR is built on a secure-by-design principle.
Approved researchers will be able to access and analyse data within trusted NHS environments, without data leaving NHS systems.
This enables:
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Safe, governed data access
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Large-scale multi-site research
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Standardised, high-quality datasets
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Reduced fragmentation of MS clinical data
FROM DATA TO IMPACT
UKNR will enable:
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Better understanding of disease progression
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Improved prediction of treatment response and side effects
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More personalised treatment strategies
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Stronger evidence for clinical decision-making
CURRENT STATUS
UKNR is currently in development, with foundational work underway across governance, data architecture, and UK-wide integration.